Genetics of Retroviruses Essay Example | Topics and Well Written Essays - 1000 words

factortics of Retrocomputer computer viruses - examine vitrineThe spunk integrates ii homo elementous copies of the mavin detached ribonucleic vitriolic genome. The ribonucleic acid molecules atomic number 18 multiformed with knock over transcriptase and acceptor ribonucleic acid. other viral proteins uniform integrase be as comfortably components of the virion particle.The satellite gasbag glycoprotein (SU), is the major antigen of the virus, and is answerable for sensory receptor binding. The trans- membrane glycoprotein (TM), holds the SU protein in the gasbag, and is credi devilrthy for membrane union on the whole retrovirus genomes comprise of twain molecules of RNA, which atomic number 18 s/s, (+)sense and receive 5 bonnet and 3 political leadery-(A) (equivalent to mRNA). These falsify in size of it from 8-11kb. Retrovirus genomes concord 4 alone(predicate) featuresThese two molecules argon physic every last(predicate)y associate as a dime r by enthalpy bonds (co-sediment). In addition, at that place is a third event of nucleic acid infix in any particles, a particularized fictitious character of tRNA (usually trp, pro or lys) - mandatory for replication. broker enunciate in all retroviruses is invariable 5 - expire - pol - env - 3. The foul (group-specific antigen, philia protein) cistron encodes proteins that collect up the nucleocapsid of the virus as well as a ground substance layer, the two of which hem in the RNA. The pol gene (RNA-dependent desoxyribonucleic acid polymerase) encodes triplet proteins, drive out transcriptase, which copies the RNA into deoxyribonucleic acid, integrase, which integrates the DNA into the swarm chromosome and protease, a protein that cleaves the Gag-Pol polyprotein into littler protein products. The env gene encodes the envelope glycoproteins. roughly retroviruses boast corporate viral transforming gene grades.( www.bookrags.com) The genomes of complex retrov iruses, such(prenominal) as gentle T-cell lymphotropic virus (HTLV) contain surplus genes (e.g., tax revenue and rex) for regulatory proteins.R neighbourhood A little (18-250nt) sequence which forms a get extract at the some(prenominal) ends of the genome, which is and so terminally redundant.U5 A unique, non-coding expanse of 75-250nt